Dr Mac's - Action of pesticides

Most of the problems from exposure to pesticides arise from cellular damage, which can disrupt a number of biological processes.  Normal processes can be suppressed or stopped completely, or they can be enhanced beyond normal physiologic limits and, in turn, affect other systems dependent on their controlled functions.  Cellular responses of chemical toxicants occur through both structural and metabolic mechanisms in the cell.  A single response can be elicited from an individual pesticide or a number of actions can be attributed. 

A pesticide on its own may not be toxic but in combination with another it could have an additive or synergistic.  This occurs when the combined effects of two or more chemicals are greater than the sum of the individual effects.  It may result if one chemical affects the solubility, binding, metabolism or excretion of the other.  So, while studies on the effects of individual pesticides may not indicate any detrimental actions, a combination of two or several pesticides may enhance toxicological actions.  The toxic action of some pesticides may be delayed and not manifest for years and can occur long after exposure stops.  This makes it confusing to interpret signs and symptoms that can be accredited to pesticide toxicology.

The actions of pesticides are varied and can include: